Understand Maternal
Obesity Before You Regret.
Obesity
is the root cause of many diseases and it is the major health issue for the public.
It has been linked to several health problems such as cancer, heart diseases, hypertension, etc. It also has an adverse
effect during pregnancy as it can cause complications in pregnancy by
increasing the mother's risk of having gestational
diabetes, preterm birth, preeclampsia or baby with birth defects.
Maternal
obesity is related to many severe outcomes for the infant, which can persist into adulthood such as heart disease, mortality and type-2 diabetes.
Maternal
obesity also compromises the immune system of babies. Researches have proven that pre-pregnancy maternal weight plays a significant role in the neonate's immune system. The immune system
of the babies born to obese mothers gets comprised very early in baby’s life.
The researchers analyzed the umbilical
cord blood sample of babies born to mothers who are lean, obese and overweight. It was found that
pre-pregnancy maternal weight has a major impact on the immune system of
neonate hence putting such babies at high risk for diseases such as asthma
and heart
diseases.
Several studies have linked maternal obesity
(pregnancy starting with excess weight and gaining more weight during
pregnancy) to a very high risk of asthma
and cardiovascular diseases in
children. These studies used established BMI
(Body Mass Index) category for
sorting mothers participating in the study. BMI 25 to 30 was considered as
overweight and mother with 30 or higher BMI was considered as obese.
Participating mothers were all non-smokers,
had no diabetes and had uncomplicated gestation term.
The result of this study indicated that specific immune
cells in the circulation that are monocytes
and dendritic cells, isolated from
babies born to mother with higher BMI were unable to properly respond to
bacterial antigens in comparison with babies born to lean mother. Babies born
to a mother with high BMI also showed a reduction in CD4 T-cell. These two changes found in the results can compromise
the responses to infection and vaccination.
Later it was also found that eosinophil; cells
responsible for allergic response and
asthma pathogenesis was also reduced
significantly in the umbilical cord blood of the babies who are born to obese
mom. The reason behind this observation is assumed to be that these cells have
already been moved to lungs and hence may have increased the incidence of
asthma which has been observed in children who are born to obese mother later
in life.
These researches showed the link between maternal obesity during pregnancy and neonatal immune
outcomes and how this can affect the immunity of child which can persist for
lifetime.
So, the overweight or obese woman before planning to
become pregnant should talk to their ob-gyn about their weight management. As obesity associated
with low fertility and success rate
of pregnancy so it has serious repercussions for maternal health. Obesity and weight gain have a high risk of
increasing preeclampsia, placental
abruption, and gestational diabetes. So it is very important to talk about the
ideal weight with a doctor before entering into pregnancy.
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